A Better Leukemia Drug
A new drug under development for the treatment of the childhood leukemia T-ALL has had success in the first round of pharmaceutical testing. An experimental new drug known as CAL-130 is a dual enzyme inhibitor, blocking two forms of an enzyme used in the out of control growth involved in leukemia. The drug successfully stopped the enzymes phosphoinositide-3 kinase gamma and delta in testing, effectively stopping cancer growth. Ask your oncologist about clinical trials available to you. Testing of the dual inhibitor took place first in mice, and then again in samples of leuk...
Afinitor for Non-Cancerous Kidney Tumors
The U.S. Food and Drug Administration approved Afinitor ( everolimus ), the first drug approved specifically to treat non-cancerous kidney tumors (renal angiomyolipomas ) not requiring immediate surgery in patients with tuberous sclerosis complex ( TSC ).
Menopause Linked to Osteoporosis
It's well known that osteoporosis is most common among post-menopausal women. A new study finds that women who start menopause early are at greater risk for fracture than most women. In fact, women who go through menopause before they turn 48 are twice as likely to develop osteoporosis, a disease that weakens bones and leads to fractures. The average age for menopause to start is 51. If you have premature menopause, get screened for osteoporosis. The study was conducted by Swedish researchers and published in BJOG : An International Journal of Obstetrics and Gynaecology . ...
How Melanoma Hides
The inflammation response is used by the body to signal an attack, but it turns out in at least one kind of melanoma, the cancer uses the same signal to go into hiding.
Votrient for Advanced Soft Tissue Sarcoma
The U.S. Food and Drug Administration approved Votrient ( pazopanib ) to treat patients with advanced soft tissue sarcoma who have previously received chemotherapy.
Higher Dosing Doesn't Mean Better Health
It's a common concept. If one dose works well, then two doses may work even better. This theory was tested recently in patients being treated for chronic myeloid leukemia ( CML ), and it didn't work.
A Mutated Thyroid Cancer
Some kinds of cancer are made more ominous than others by certain genetic mutations. Detecting these mutations early can help doctors know which patients to treat aggressively and early.
Smoking While Pregnant & Autism Not Linked
As the search continues for environmental factors that may contribute to the increasing autism cases, researchers are looking in every nook and cranny for possible associations.
Gene Based Drug for Acute Myeloid Leukemia
Researchers believe that targeting the cancer gene FLT3 could cure one type of leukemia, and say results from their research explain the failure of several drugs currently used. Scientists studying the genetic relationships involved in acute myeloid leukemia have used the genetic data produced in their research to refine the search for a new drug, and testing of one candidate is underway. Ask your oncologist about clinical trials available to you. The group from the University of California in San Francisco announced that the gene FLT3 was being investigated as a possible target...
Do Concrete and Smog Create Heart Risks?
Living in a big city may have its benefits when it comes to convenience, but a new study reveals added pollution may not be doing any favors for your heart.