Tyrvaya

Tyrvaya is a prescription nasal spray used to treat the signs and symptoms of dry eye disease.

Tyrvaya belongs to a group of drugs called cholinergic agonists. It is believed to increase tear production in the eye by binding to certain receptors that activate the trigeminal parasympathetic pathway.

This medication comes as a nasal spray. The recommended adult dose is 1 spray in each nostril, 2 times daily (about 12 hours apart).

Common side effects include sneezing, cough, and throat and nose irritation.

Tyrvaya is a prescription medication used to treat the signs and symptoms of dry eye disease.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

The most common side effects of Tyrvaya include sneezing, cough, and throat and nose irritation.

These are not the only possible side effects of Tyrvaya. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Tyrvaya there are no specific foods that you must exclude from your diet when receiving this medication.

Before you use Tyrvaya, tell your healthcare provider about all of your medical conditions, including if you: 

• are pregnant or plan to become pregnant. It is not known if Tyrvaya will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if Tyrvaya passes into your breast milk. You and your healthcare provider should decide if you will use Tyrvaya if you plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Tyrvaya will harm your unborn baby.

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Tyrvaya crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Tyrvaya.

• Tyrvaya increases tear production in the eye after being sprayed in the nose.
• Use Tyrvaya exactly as your healthcare provider tells you to use it.
• Do not shake the bottles.
• Spray Tyrvaya 1 time in each nostril, 2 times daily (about 12 hours apart).
• A 1-month supply of Tyrvaya consists of 2 nasal spray bottles. Finish 1 bottle before opening the second. Tyrvaya comes in glass bottles with a white nasal pump and blue dust cover.
• If you miss a dose of Tyrvaya, skip that dose and take your next dose at your regular scheduled time. Do not take an extra dose to make up for a missed dose.

The recommended dose of Tyrvaya is 1 spray in each nostril twice daily (12 hours apart).

If you take too much Tyrvaya, call your healthcare provider or emergency medical attention right away.