Risperdal

Risperdal is used to treat the symptoms of schizophrenia. Risperdal can cause weight gain and can increase cholesterol levels, blood sugar, and blood pressure.

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Pharmacist Trey Robinson, PharmD summarizes the uses, common side effects, and warnings for the Atypical antipsychotics class of medications
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Pharmacist Trey Robinson, PharmD summarizes the uses, common side effects, and warnings for the Atypical antipsychotics class of medications
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Risperdal Overview

Updated: 

Risperdal is a prescription medication used to treat schizophrenia. It is also used to treat manic or mixed episodes associated with Bipolar I Disorder. Risperdal also is used to treat behavioral symptoms associated with autism. Risperdal belongs to a group of drugs called atypical antipsychotics. It is not fully known how it works, but it is believed to work by changing the activity of natural substances in the brain.

Risperdal comes as a tablet and in an oral solution. It is usually taken once or twice a day with or without food. 

Common side effects of Risperdal are headache, increased appetite, tremors, and dizziness.

How was your experience with Risperdal?

First, a little about yourself

Tell us about yourself in a few words?

What tips would you provide a friend before taking Risperdal?

What are you taking Risperdal for?

Choose one
  • Other
  • Autistic Disorder
  • Bipolar Disorder
  • Dementia
  • Schizophrenia
  • Schizophrenia And Disorders With Psychotic Features
  • Tourette Syndrome

How long have you been taking it?

Choose one
  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

How well did Risperdal work for you?

Did you experience many side effects while taking this drug?

How likely would you be to recommend Risperdal to a friend?

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Risperdal Cautionary Labels

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Uses of Risperdal

Risperdal is a prescription medication used to treat schizophrenia. It is also used to treat manic or mixed episodes associated with Bipolar I Disorder. Risperdal also is used to treat behavioral symptoms associated with autism.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Risperdal Drug Class

Risperdal is part of the drug class:

Side Effects of Risperdal

Common side effects of Risperdal include the following:

  • drowsiness
  • dizziness
  • nausea
  • vomiting
  • diarrhea
  • constipation
  • heartburn
  • dry mouth
  • increased saliva
  • increased appetite
  • weight gain
  • stomach pain
  • anxiety
  • agitation
  • restlessness
  • dreaming more than usual
  • difficulty falling asleep or staying asleep
  • decreased sexual interest or ability
  • breastmilk production
  • vision problems
  • muscle or joint pain
  • dry or discolored skin
  • difficulty urinating

Risperdal Interactions

Tell your doctor about the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take: 

  • antidepressants
  • carbamazepine (Tegretol)
  • cimetidine (Tagamet)
  • clozapine (Clozaril)
  • dopamine agonists such as bromocriptine (Parlodel), cabergoline (Dostinex), levodopa (Dopar, Larodopa), pergolide (Permax), and ropinirole (Requip)
  • medications for anxiety, high blood pressure, or seizures
  • other medications for mental illness
  • paroxetine (Paxil)
  • phenobarbital (Luminal, Solfoton)
  • phenytoin (Dilantin)
  • quinidine (Quinaglute, Quinidex)
  • ranitidine (Zantac)
  • rifampin (Rifadin, Rimactane)
  • sedatives
  • sleeping pills
  • tranquilizers
  • valproic acid (Depakote, Depakene)

This is not a complete list of Risperdal drug interactions. Ask your doctor or pharmacist for more information.

Risperdal Precautions

  • Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as Risperdal have an increased risk of death during treatment. Older adults with dementia may also have a greater chance of having a stroke or mini-stroke during treatment. Tell your doctor and pharmacist if you are taking furosemide (Lasix).
  • Risperdal is not approved by the Food and Drug Administration (FDA) for the treatment of behavior problems in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is taking Risperdal.
  • Other serious side effects that require medical attention include the following:
    • fever
    • muscle stiffness
    • confusion
    • fast or irregular pulse
    • sweating
    • unusual movements of your face or body that you cannot control
    • faintness
    • seizures
    • slow movements or shuffling walk
    • rash
    • hives
    • itching
    • difficulty breathing or swallowing
    • painful erection of the penis that lasts for hours

Risperdal may cause children to gain more weight than expected and for boys and male teenagers to have an increase in the size of their breasts. Talk to your doctor about the risks of giving this medication to your child.

Risperdal Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Risperdal there are no specific foods that you must exclude from your diet when receiving Risperdal.

Inform MD

Before receiving Risperdal, tell your doctor about all of your medical conditions including if you have:

  • Parkinson's Disease
  • breast cancer
  • heart disease (angina, irregular heartbeat, heart failure, heart attack, stroke)
  • high blood pressure
  • low blood pressure
  • a history of seizures
  • kidney disease
  • liver disease
  • diabetes

Tell your doctor if you are allergic to any ingredient in Risperdal.

Be sure to tell your doctor if you are pregnant or breastfeeding.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Risperdal and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

This medication falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Risperdal and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. Risperdal can cross into human breast milk. It may harm your baby.

Risperdal Usage

  • Risperdal comes as a tablet and in an oral solution (liquid) to take by mouth.
  • It is usually taken once or twice a day with or without food. Take Risperdal at around the same time(s) every day.
  • Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
  • Take Risperdal exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Risperdal Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your weight
  • your height
  • your age
  • your gender

Schizophrenia in Adults - The recommended dose range is 2 to 16 mg. 

Schizophrenia in Adolescents - The recommended dose range is 0.5 to 6 mg. 

Bipolar Mania in Adults - The recommended dose range is 2 to 6 mg. 

Bipolar Mania in Children and Adolescents - The recommended dose range is 0.5 to 6 mg.

Irritability associated with autistic disorder - The recommended dose range is 0.25 to 3 mg (if you weigh less than 20 kg) OR 0.5 to 3 mg (if you weight 20 kg or greater).

Risperdal Overdose

If you take too much this medication, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Other Requirements

  • Risperdal Tablets should be stored at controlled room temperature 15°–25°C (59°–77°F). Protect from light and moisture.
  • Risperdal Oral Solution should be stored at controlled room temperature 15°–25°C (59°–77°F). Protect from light and freezing.
  • Keep out of reach of children.

Risperdal FDA Warning

WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS

Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of 17 placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular (e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. Risperdal is not approved for the treatment of patients with dementia-related psychosis.