Pentoxil

Pentoxil is a prescription medication used to reduce the symptoms of intermittent claudication (pain in the legs when walking due to narrowing of blood vessels). Pentoxil belongs to a group of drugs called methylxanthine derivatives, which improve blood flow by decreasing the thickness of blood.

This medication comes in tablet form and is usually taken 3 times a day, with meals.

Common side effects of Pentoxil include upset stomach, vomiting, gas, and headache. Pentoxil can also cause dizziness. Do not drive or operate heavy machinery until you know how Pentoxil affects you.

Pentoxil is a prescription medication used to reduce the symptoms of intermittent claudication (pain in the legs when walking due to narrowing of blood vessels).

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

• Upsher-Smith Laboratories, Inc.

Serious side effects have been reported with Pentoxil. See the “Drug Precautions” section.

Common side effects include:

• upset stomach
• vomiting
• gas
• dizziness
• headache
• chest pain
• fast heartbeat

This is not a complete list of Pentoxil side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• anticoagulants or platelet aggregation inhibitors, especially warfarin (Coumadin)
• drugs that contain theophylline
• drugs that contain captopril (Capoten, Capozide) or nifedipine (Adalat, Adalat CC, Afeditab CR, Procardia, Procardia XL)

This is not a complete list of Pentoxil drug interactions. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Pentoxil including the following:

• chest pain
• fast heartbeat

Pentoxil can cause dizziness and drowsiness. Do not drive or operate heavy machinery until you know how this medication affects you.

Do not take Pentoxil if you:

• are allergic to Pentoxil or to any of its ingredients or to other methylxanthine derivatives, including caffeine, theophylline, and theobromine
• have had a recent cerebral and/or retinal hemorrhage

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Pentoxil, there are no specific foods that you must exclude from your diet when receiving this medication.

Before taking Pentoxil, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

• are allergic to Pentoxil or to any of its ingredients or to other methylxanthine derivatives, including caffeine, theophylline, and theobromine
• have had a recent cerebral and/or retinal hemorrhage
• have or have had kidney disease
• are having surgery, including dental surgery
• are pregnant or plan to become pregnant
• are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Pentoxil falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans, though. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Tell your doctor if you are breastfeeding or plan to breastfeed.

Pentoxil has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from Pentoxil, a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.

Take Pentoxil exactly as prescribed.

Pentoxil comes in tablet form and is usually taken three times every day.

Take with meals to avoid an upset stomach.

Do not chew, divide, or break Pentoxil tablets. Swallow tablets whole.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Pentoxil at the same time.

Take Pentoxil exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Pentoxil dose your doctor recommends will be based on the following:

• the condition being treated
• other medical conditions you have
• other medications you are taking
• how you respond to this medication
• your age

The recommended dose range for Pentoxil (pentoxifylline) is 400 mg three times a day.

If you take too much Pentoxil, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

• Store Pentoxil at room temperature. Temperature may vary between 15-30°C (59-86°F).
• Store Pentoxil away from excess heat and moisture. Do not store it in the bathroom.
• Keep this and all medicines out of the reach of children.