Xibrom

Xibrom is a prescription medication used to treat eye inflammation in patients who have undergone cataract surgery. Xibrom belongs to a group of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It works by stopping the release of certain natural substances that cause pain and swelling.

This medication comes in the form of an eye drop to be given twice a day beginning 24 hours after surgery and for 14 days after surgery. 

Common side effects in clinical trials include eye pain, blurred vision, and the feeling of "something in the eye" (foreign body sensation).

Xibrom is a prescription medication used to treat eye inflammation in patients who have undergone cataract surgery.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

• Ista Pharmaceuticals, Inc.

Serious side effects have been reported with Xibrom. See “Drug Precautions” section.

Common side effects include:

• eye pain
• eye irritation (including burning/stinging)
• itching of the eye
• eye redness
• headache
• blurred vision
• feeling of "something in the eye" (foreign body sensation)

This is not a complete list of Xibrom side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Xibrom does not have any listed drug interactions. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Xibrom including:

• Sulfite Allergic Reactions: Contains a sulfite that may cause allergic type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in people with this allergy.
• Slow or Delayed Healing: All topical nonsteroidal anti-inflammatory drugs (NSAIDs), including Xibrom, may slow or delay healing.
• Potential for Cross-Sensitivity: There is the potential for cross-sensitivity to aspirin and other NSAIDs, including Xibrom. Therefore, caution should be used if you have previously exhibited sensitivities to these drugs.
• Increased Bleeding Time: With some NSAIDs, including Xibrom, increased bleeding time may be possible, especially when it is given after surgery. Xibrom should be used with caution in those with known bleeding tendencies or who are receiving blood thinners
• Keratitis and Corneal (front layer part of the eye) Reactions: Use of Xibrom may result in keratitis (inflammation of the eye). Long-term use of Xibrom may also result in eye damage, leading to loss of sight. Patients with changes in eyesight should immediately discontinue use of topical Xibrom.
• Loss of sight: Those with complicated ocular surgeries, eye defects or damage, diabetes, eye diseases (such as dry eye syndrome), rheumatoid arthritis, or repeat ocular surgeries within a short period of time may be at increased risk for eye problems which may result in loss of sight. Xibrom should be used with caution in these patients.
• Eye Surgery Precaution: Use of Xibrom more than 24 hours before surgery or beyond 14 days after surgery may increase risk for the occurrence and severity of corneal (front layer of the eye) adverse events.

Xibrom can cause blurred vision. Do not drive or operate heavy machinery until you know how Xibrom affects you.

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Xibrom, there are no specific foods that you must exclude from your diet when receiving Xibrom.

Before taking Xibrom, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

• have a sulfa allergy
• have had an allergic reaction to this medication before, to any other NSAID, or to aspirin (Ecotrin)
• have eye defects, damage, or dysfunction
• have rheumatoid arthritis
• have or have had other recent ocular surgeries
• have diabetes
• take blood thinners
• are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Xibrom falls into category C. There are no well-done studies in pregnant women. The use of Xibrom during late pregnancy should be avoided. Xibrom should be given to a pregnant woman only if clearly needed.

Tell your doctor if you are breastfeeding or plan to breastfeed.

Caution should be used when Xibrom is given to a nursing (breastfeeding) woman.
 

Use Xibrom exactly as prescribed.

This medication comes in the form of an eye drop to be given twice a day beginning 24 hours after surgery and for 14 days after surgery. 

Xibrom should not be given while wearing contact lenses. Remove contact lenses before using Xibrom. 

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Xibrom at the same time.

Use Xibrom exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

Insert one eye drop into the affected eye(s) twice daily, beginning 24 hours after surgery and for 14 days after surgery. 

If you use too much Xibrom, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Store Xibrom at 15-25°C (59-77°F).

Keep this and all medicines out of the reach of children.