Medrol

Medrol is a prescription medication used to treat many conditions including low corticosteroid levels (adrenal insufficiency), certain types of arthritis, allergic conditions, multiple sclerosis, lupus, and other diseases affecting the lungs, skin, eyes, kidneys, blood, thyroid, stomach, and intestines.

Medrol belongs to a group of drugs called corticosteroids, which replace corticosteroids which the body normally make, or to reduce inflammation that could cause damage to the body.

This medication comes in tablet form. It is best taken with food to prevent stomach upset.

Common side effects include upset stomach, dizziness, and difficulty falling asleep.  Do not drive or operate machinery until you know how it will affect you.

 

Medrol is a prescription medication used to treat:

• arthritis
• allergic conditions
• asthma
• certain conditions affecting the lungs, skin, eyes, kidneys, blood, thyroid, stomach, and intestines. Medrol frequently treats diseases of these organs by reducing inflammation.
• some types of cancer

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Take Medrol exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

Your doctor will determine the appropriate dosage and schedule depending the disease being treated and your response to the medication. The starting dosage of Medrol may vary from 4 mg to 48 mg a day depending on reason for use.

Serious side effects have been reported with Medrol including:

• Hypersensitivity reaction: Medrol may trigger an allergic response. Symptoms of a hypersensitivity reaction include:
  • hives
  • difficulty breathing or swallowing
  • swelling
  • rash
  • itching
• Cardiac and renal problems: Medrol can increase blood pressure, cause water and sodium retention, and increase potassium and calcium excretion. Tell your doctor if you have a history of heart or kidney disease.
• Immunosuppression: Medrol decreases your body’s immune response to infections. In addition, Medrol can increase sensitivity to vaccines since the immune response is reduced with Medrol use.
• Reactivation of tuberculosis: Tell your doctor if you have had tuberculosis.
• Perforation of the gastrointestinal tract: Medrol can cause holes in the stomach or intestinal lining.  Tell your doctor if you have a history of ulcers or other digestive system problems.
• Decreased bone formation: Medrol can prevent the formation of bones, which may result in decreased bone density and osteoporosis.
• Eye damage: Long-term use may lead to cataracts, glaucoma, damage to the optic (eye) nerves, and may worsen an eye infection.
• Electrolyte changes: Corticosteroids can cause a rise sodium and a decrease of potassium. Corticosteroids also cause a loss in calcium.
• Extreme mood changes: Tell your healthcare provider right away if you have some or all of the following symptoms...
  • euphoria (intense feeling of happiness or joy)
  • insomnia
  • mood swings
  • personality changes
  • severe depression
• Stunted growth in children: Growth should be monitored with long-term use of Medrol.
• Kaposi's sarcoma: This type of cancer has been reported to occur in patients receiving corticosteroid therapy. Stopping its use may result in clinical remission.
• Steroid withdrawal: To avoid withdrawal side effects, do not stop taking Medrol suddenly. Discuss with your doctor about slowly decreasing the dose before stopping use of this medication altogether.

Medrol can cause dizziness. Do not drive or operate heavy machinery until you know how Medrol affects you.

Do not take Medrol if you:

• have an active fungal infection
• are allergic to Medrol, aspirin, or any ingredient within this medication product

Serious side effects have been reported with Medrol. See “Medrol Precautions” section.

Common side effects of Medrol include:

• upset stomach
• stomach irritation
• vomiting
• headache
• dizziness
• insomnia
• restlessness
• depression
• anxiety
• acne
• increased hair growth
• easy bruising
• irregular or absent menstrual periods

This is not a complete list of Medrol side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• cyclosporine (Sandimmune, Neoral, Restasis, Gengraf)
• phenobarbital (Donnatal)
• phenytoin (Dilantin)
• rifampin (Rifadin, Rimactane)
• ketoconazole (Nizoral)
• aspirin (Ecotrin)

This is not a complete list of Medrol drug interactions. Ask your doctor or pharmacist for more information.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Medrol falls into category C. This medication may be given to a pregnant woman if her healthcare provider believes that its benefits to the pregnant woman outweigh any possible risks to her unborn baby.

It is not known if Medrol will harm your unborn baby.

Tell your doctor if you are breastfeeding or plan to breastfeed.

You should not take Medrol if you are breastfeeding. It may be excreted in your breast milk and may harm your nursing child.

To avoid withdrawal side effects, do not stop taking methylprednisolone suddenly.

Tell your doctor if you have are or about to receive a vaccine, especially a live one such as the nasal influenza, MMR, or varicella vaccines.

Although methylprednisolone tablets can be taken with or without food, it is recommended to take with food to prevent stomach irritation.