Lipitor

Lipitor lowers cholesterol. May interact with grapefruit and grapefruit juice.

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Pharmacist Beth Bolt, RPh overviews the uses and common side effects of Lipitor
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Pharmacist Beth Bolt, RPh overviews the uses and common side effects of Lipitor
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Lipitor Overview

Updated: 

Lipitor is a prescription medicine used to treat high cholesterol levels and to prevent heart disease. Lipitor belongs to a group of drugs called HMG-CoA reductase inhibitors, also known as statins. Lipitor works by blocking the production of cholesterol in the body.

This medication comes in tablet form and is usually taken once a day, with or without food.
 
Common side effects of Lipitor include diarrhea, upset stomach, and muscle and joint pain.

How was your experience with Lipitor?

First, a little about yourself

Tell us about yourself in a few words?

What tips would you provide a friend before taking Lipitor?

What are you taking Lipitor for?

Choose one
  • Other
  • Coronary Artery Disease
  • Hypercholesterolemia
  • Hyperlipoproteinemias
  • Hypertriglyceridemia

How long have you been taking it?

Choose one
  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

How well did Lipitor work for you?

Did you experience many side effects while taking this drug?

How likely would you be to recommend Lipitor to a friend?

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Lipitor Cautionary Labels

precautionsprecautionsprecautionsprecautionsprecautions

Uses of Lipitor

Lipitor is a prescription medicine used to treat adults and children at least 10 years of age with high cholesterol that cannot be controlled by exercise and a low-fat diet alone. Lipitor is also used to prevent heart disease.

This medication may be prescribed for other uses.  Ask your doctor or pharmacist for more information.

Manufacturer

Lipitor Drug Class

Lipitor is part of the drug class:

Side Effects of Lipitor

Lipitor can cause serious side effects. These side effects have happened only to a small number of people. Your doctor can monitor you for them. These side effects usually go away if your dose is lowered or Lipitor is stopped. These serious side effects include:

  • Muscle problems. Lipitor can cause serious muscle problems that can lead to kidney problems, including kidney failure. You have a higher chance for muscle problems if you are taking certain other medicines with Lipitor.
  • Liver problems. Your doctor should do blood tests to check your liver before you start taking Lipitor and if you have symptoms of liver problems while you take Lipitor. Call your doctor right away if you have the following symptoms of liver problems:
    • feel tired or weak
    • loss of appetite
    • upper belly pain
    • dark amber colored urine
    • yellowing of your skin or the whites of your eyes

Call your doctor right away if you have:

  • muscle problems like weakness, tenderness, or pain that happen without a good reason, especially if you also have a fever or feel more tired than usual.
  • allergic reactions including swelling of the face, lips, tongue, and/or throat that may cause difficulty in breathing or swallowing which may require treatment right away.
  • nausea and vomiting.
  • passing brown or dark-colored urine.
  • you feel more tired than usual
  • your skin and whites of your eyes get yellow.
  • stomach pain.
  • allergic skin reactions.

In clinical studies, patients reported the following common side effects while taking Lipitor: the common cold (known as nasopharyngitis), joint pain, diarrhea, pain in extremeties, and urinary tract infections.

The following additional side effects have been reported with Lipitor:

  • general feeling of discomfort (malaise)
  • fever
  • neck pain
  • joint swelling
  • hives

Talk to your doctor or pharmacist if you have side effects that bother you or that will not go away.

These are not all the side effects of Lipitor. Ask your doctor or pharmacist for a complete list.

Lipitor Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • antifungal medications such as itraconazole (Sporanox) and ketoconazole (Nizoral)
  • cimetidine (Tagamet)
  • clarithromycin (Biaxin)
  • colchicine (Colcrys)
  • digoxin (Lanoxin)
  • diltiazem (Cardizem, Cartia, Taztia, Tiazac)
  • erythromycin (E.E.S., E-Mycin, Erythrocin)
  • efavirenz (Sustiva, in Atripla)
  • oral contraceptives (birth control pills)
  • other cholesterol-lowering medications such as fenofibrate (Tricor), gemfibrozil (Lopid), and niacin (nicotinic acid, Niacor, Niaspan)
  • certain HIV protease inhibitors such as darunavir (Prezista), fosamprenavir (Lexiva), lopinavir (in Kaletra), nelfinavir (Viracept), saquinavir (Invirase), ritonavir (Norvir, in Kaletra) and tipranavir (Aptivus)
  • medications that suppress the immune system such as cyclosporine (Neoral, Sandimmune)
  • rifampin (Rifadin, Rimactane)
  • spironolactone (Aldactone)
  • telaprevir (Incivek)

This is not a complete list of Lipitor drug interactions. Ask your doctor or pharmacist for more information.

Lipitor Precautions

Statin medications, including Lipitor, carry a rare but serious risk of:

  • liver damage
  • memory loss or confusion
  • increase in blood sugar levels (hyperglycemia)
  • type 2 diabetes
  • immune-mediated muscle breakdown

Certain statins can increase risk of muscle weakness as well.  It is important to consult your physician to discuss the benefits and risks associated with using this medication.

Do not take Lipitor if you:

  • are pregnant or think you may be pregnant, or are planning to become pregnant. Lipitor may harm your unborn baby. If you get pregnant, stop taking Lipitor and call your doctor right away.
  • are breastfeeding. Lipitor can pass into your breast milk and may harm your baby.
  • have liver problems.
  • are allergic to Lipitor or any of its ingredients. 

Lipitor has not been studied in children under 10 years of age.

  • Talk to your doctor before you start any new medicines. This includes prescription and non-prescription medicines, vitamins, and herbal supplements. Lipitor and certain other medicines can interact causing serious side effects.
  • Do not get pregnant. If you get pregnant, stop taking Lipitor right away and call your doctor.

Lipitor Food Interactions

Grapefruit and grapefruit juice may interact with Lipitor and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

Inform MD

Tell your doctor if you:

  • have muscle aches or weakness
  • drink more than 2 glasses of alcohol daily
  • have diabetes
  • have a thyroid problem
  • have kidney problems

Some medicines should not be taken with Lipitor. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Lipitor and certain other medicines can interact causing serious side effects. Especially tell your doctor if you take medicines for:

  • your immune system
  • cholesterol
  • infections
  • birth control
  • heart failure
  • HIV or AIDS

Lipitor and Pregnancy

Tell your doctor if you are pregnant or think you may be pregnant, or are planning to become pregnant. Lipitor may harm your unborn baby. If you get pregnant, stop taking Lipitor and call your doctor right away.

 

Lipitor and Lactation

Tell your doctor if you are breastfeeding. Lipitor can pass into your breast milk and may harm your baby.

 

Lipitor Usage

  • Take Lipitor exactly as prescribed by your doctor. Do not change your dose or stop Lipitor without talking to your doctor. Your doctor may do blood tests to check your cholesterol levels during your treatment with Lipitor. Your dose of Lipitor may be changed based on these blood test results.
  • Take Lipitor each day at any time of day at about the same time each day. Lipitor can be taken with or without food. Don't break Lipitor tablets before taking.
  • Your doctor should start you on a low-fat diet before giving you Lipitor. Stay on this low-fat diet when you take Lipitor.
  • If you miss a dose of Lipitor, take it as soon as you remember. Do not take Lipitor if it has been more than 12 hours since you missed your last dose. Wait and take the next dose at your regular time. Do not take 2 doses of Lipitor at the same time.

Lipitor Dosage

The Lipitor dose your doctor recommends will depend on several factors including your age, the medical condition being treated, other medical conditions you have, and the medications you are taking.

The recommended starting Lipitor dose is 10 or 20 mg once daily. For some people with extremely high cholesterol, the starting Lipitor dose may be as high as 40 mg.

After several weeks the Lipitor dose may be increased as necessary to achieve the desired cholesterol levels. If you are experiencing side effects, your doctor may reduce your Lipitor dose. The recommended dosage range of Lipitor is 10 to 80 mg once daily.

For children (ages 10 to 17), the maximum recommended daily Lipitor dose is 20 mg.

Lipitor Overdose

If you take too much Lipitor or overdose, call your doctor or Poison Control Center right away. Or go to the nearest emergency room.

Other Requirements

  • Store Lipitor at room temperature, 68 to 77°F (20 to 25°C).
  • Do not keep medicine that is out of date or that you no longer need.
  • Keep Lipitor and all medicines out of the reach of children. Be sure that if you throw medicine away, it is out of the reach of children.