Medication

Detrol

Generic name: tolterodine

Pharmacist-reviewed drug information from the RxWiki encyclopedia.

Overview

Detrol is a prescription medication used to treat the symptoms of an overactive bladder in adults. Detrol belongs to a group of drugs called antimuscarinic medications, which help the bladder muscles to relax.

This medication comes in an immediate-release tablet form and is usually taken twice a day with or without food.

Common side effects of Detrol include dry mouth, dizziness, and headache.

What is it used for?

Detrol is a prescription medicine for adults used to treat the following symptoms due to a condition called overactive bladder:

  • urge urinary incontinence: a strong need to urinate with leaking or wetting accidents
  • urgency: a strong need to urinate right away
  • frequency: urinating often

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

How to take it

Take Detrol exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The initial recommended dose of Detrol is 2 mg twice daily. The dose may be lowered to 1 mg twice daily based on how you respond to and tolerate Detrol.

Dosage Adjustment in Specific Populations

For patients with reduced liver or kidney function or who are currently taking certain drugs that can affect how Detrol works in the body, the recommended dose of Detrol is 1 mg twice daily.

Warnings

Do not take Detrol if you

  • are not able to empty your bladder (urinary retention)
  • have delayed or slow emptying of your stomach (gastric retention)
  • have an eye problem called "uncontrolled narrow-angle glaucoma"
  • are allergic to Detrol or to any of its ingredients
  • are allergic to Toviaz, which contains fesoterodine

Medicines like Detrol can cause blurred vision or drowsiness. Use caution while driving or doing other dangerous activities until you know how Detrol affects you.

Side effects

The most common side effects with Detrol are:

  • dry mouth
  • dizziness
  • headache
  • stomach pain
  • constipation

This is not a complete list of side effects of Detrol. Talk to your doctor about any side effect that is bothersome or does not go away.

Drug interactions

Tell your doctor about all the medicines you take or are planning to take includine prescription and non-prescription medicines, vitamins, and herbal supplements. If you take Detrol with other medicines, the effects of either could be increased, decreased, or altered. Especially tell your doctor if you take:

  • clarithromycin
  • cyclosporin
  • erythromycin
  • itraconazole
  • ketoconazole
  • miconazole
  • vinblastine

This is not a complete list of Detrol drug interactions. Ask your doctor or pharmacist for more information.

Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

This medication falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Breastfeeding

Tell your doctor if you are breastfeeding or if you are planning to breastfeed. It is not known if Detrol is excreted in human breast milk or if it will harm your nursing baby.

Quick facts

Tolterodine long-acting capsules should be swallowed whole with a glass of water.

Medicines like tolterodine can cause blurred vision or drowsiness. Use caution while driving or doing other dangerous activities until you know how tolterodine affects you.

Before starting tolterodine, tell your doctor if you are being treated for an eye problem called narrow-angle glaucoma.

All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.