ConZip is used for moderate to moderately severe pain. It also has weak antidepressant effects. ConZip may not be suitable in people with a history of seizures.
ConZip is a prescription medication used to treat moderate to moderately severe chronic pain in adults. ConZip belongs to a group of drugs called opioid analgesics, which work by blocking pain signals in the body.
ConZip comes in extended-release capsule form and is taken once a day, with liquid. Do not chew, divide, or break ConZip capsules. Swallow the capsules whole.
Common side effects of ConZip include nausea, constipation, dry mouth, and fatigue. ConZip can also cause dizziness or drowsiness. Do not drive or operate heavy machinery until you know how ConZip affects you.
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ConZip Cautionary Labels
Uses of ConZip
ConZip is a prescription medication used to treat moderate to moderately severe chronic pain.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
ConZip Drug Class
ConZip is part of the drug class:
Side Effects of ConZip
Serious side effects have been reported with ConZip. See "Drug Precautions" section.
Common side effects of ConZip include:
- itching skin
- loss of appetite
- difficulty falling or staying asleep
This is not a complete list of ConZip side effects. Ask your doctor or pharmacist for more information.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- digoxin (Lanoxin)
- warfarin (Coumadin, Jantoven)
- central nervous system depressants such as alcohol, tranquilizers, or sedative hypnotics
- other opioid medications such as hydrocodone (Vicodin) or oxycodone (Oxycontin)
- medications that block the enzyme CYP3A4 such as some macrolide antibiotics (clarithromycin, telithromycin), some HIV protease inhibitors (indinavir, nelfinavir, ritonavir, saquinavir), some HCV protease inhibitors (boceprevir, telaprevir), some azole antifungals (ketoconazole, itraconazole, posaconazole, voriconazole), conivaptan (Vaprisol), delavirdine (Rescriptor), and nefazodone (Serzone)
- medications that increase the activity of the enzyme CYP3A4 such as carbamazepine (Tegretol, Equetro, Carbatrol), phenobarbital, phenytoin (Dilantin), rifampin, St John's wort, and nimodipine (Nimotop)
- medications that block the enzyme CYP2D6 such as quinidine (Qualaquin), fluoxetine (Prozac, Sarafem), amitriptyline (Elavil, Amitril), and paroxetine (Paxil)
- triptans such as sumatriptan (Imitrex, Treximet), eletriptan (Relpax), almotriptan (Axert), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), and zolmitriptan (Zomig)
- monoamine oxidase inhibitors such as tranylcypromine (Parnate), phenelzine (Nardil), selegiline (Eldepryl, Zelapar), isocarboxazid (Marplan), and rasagiline (Azilect)
- selective serotonin reuptake inhibitors (SSRIs) such as escitalopram (Lexapro), sertraline (Zoloft), citalopram (Celexa), paroxetine (Paxil), fluoxetine (Prozac, Sarafem), and fluvoxamine (Luvox)
- tricyclic antidepressants such as trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), and clomipramine (Anafranil)
- other tricyclic compounds such as cyclobenzaprine (Flexeril) and promethazine (Phenergan)
This is not a complete list of ConZip drug interactions. Ask your doctor or pharmacist for more information.
Serious side effects have been reported with ConZip including the following:
- seizures. Tell your healthcare provider right away if you have some or all of the following symptoms of seizures:
- body convulsions (shaking and trembling)
- temporary loss of consciousness
- serotonin syndrome. Tell your healthcare provider right away if you have some or all of the following symptoms of serotonin syndrome:
- fast heart rate
- overactive reflexes
- high blood pressure
- restlessness or agitation
- nausea or vomiting
- decline in muscle coordination
- rise in body temperature
- discontinuation symptoms. Do not stop ConZip without first talking to your healthcare provider. Stopping ConZip suddenly may cause serious symptoms including the following:
- shaking or shivering
- upper airway symptoms
- goose bumps
- rarely hallucinations
ConZip can cause dizziness or drowsiness. Do not drive or operate heavy machinery until you know how ConZip affects you.
Avoid drinking alcohol while taking ConZip.
Do not take ConZip if you:
- are allergic to ConZip or any of its ingredients
- have a history of respiratory depression in unmonitored settings or the absence of corrective measures
- have a history of acute or chronic bronchial asthma or hypercapnia in unmonitored settings or the absence of corrective measures
ConZip Food Interactions
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of ConZip, there are no specific foods that you must exclude from your diet when receiving ConZip..
Before taking ConZip, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
- are allergic to ConZip or to any of its ingredients
- have respiratory problems
- have a history of seizures or are at risk of seizures
- have medical problems with your digestive tract
- have or have had depression
- are suicidal or have had suicidal thoughts
- have a history of substance or alcohol abuse
- are consuming large amounts of alcohol
- have liver problems
- have kidney problems
- are pregnant or breastfeeding
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
ConZip and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
ConZip falls into category C. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.
ConZip and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed.
ConZip has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from ConZip, a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.
TakeConZip exactly as prescribed.
ConZip comes in extended-release capsule form and is taken once a day, with liquid.
Do not chew, divide, or break ConZip extended-release capsules.
If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of ConZip at the same time.
Take ConZip exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
The ConZip dose your doctor recommends will be based on the following:
- the severity of your pain
- other medical conditions you have
- other medications you are taking
- how you respond to this medication
- your age
The recommended dose range of ConZip (tramadol) extended-release capsules is 100 to 300 mg once every day.
If you take too much ConZip, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.
If ConZip is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.
- Store ConZip between 59°F to 86°F (15°C to 30°C).
- Keep ConZip and all medicines out of the reach of children.