When traditional drugs fail to reduce the pain of osteoarthritis, doctors may put patients on anti-tumor necrosis factor (anti-TNF) medications. But at least one anti-TNF drug may not relieve pain either.

Rheumatoid Arthritis (RA) increases a person's risk for some types of cancer such as lymphoma and lowers the risk of other types such as colon and breast. Now, it seems medications for RA increase the risk for another kind of cancer.