Bryhali

Bryhali is a prescription medication used to treat adults with plaque psoriasis. Bryhali comes in a low-concentration formulation designed to limit exposure to the negative side effects of steroids which may include thinning of skin (atrophy), stretch marks (striae), spider veins (telangiectasia), lightened skin (hypopigmentation) and rash (allergic contact dermatitis).

Bryhali belongs to a group of drugs called topical corticosteroids. It works by activating certain molecules in the skin to reduce swelling, redness, and itching.

This medication comes as a topical lotion. Apply a thin layer to the affected area once daily. Do not use Bryhali on the face, groin or armpits. Wash hands after application unless you are using the medicine to treat your hands.

Common side effects include reddening, itching, and swelling at application site.

Bryhali is a topical corticosteroid prescription medication used to treat adults with plaque psoriasis.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Bryhali. See the “Bryhali Precautions” section.

Common side effects of Bryhali include:

• burning, stinging, itching, dryness (application site dermatitis)
• upper respiratory tract infection
• high blood sugar (hyperglycemia)

This is not a complete list of Bryhali side effects.

Ask your doctor or pharmacist for more information. Tell your doctor if you have any side effects that bother you or that do not go away. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

No drug interactions have been determined by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Serious side effects have been reported with Bryhali including the following:

• Bryhali can pass through your skin. Too much Bryhali passing through your skin can cause adrenal glands to stop working.
• Cushing’s syndrome, a condition that happens when your body is exposed to too much of the hormone cortisol.
• High blood sugar (hyperglycemia).
• Skin reactions at the treated skin site. Tell your doctor if you get any skin reactions or skin infections.
• Vision problems. Bryhali may increase your chance of developing cataract(s) and glaucoma. Tell your healthcare provider if you develop blurred vision or other vision problems during treatment with Bryhali.
• Effects on growth and weight in children.

Do not take Bryhali if you are allergic to Bryhali or to any of its ingredients.

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Bryhali, there are no specific foods that you must exclude from your diet when receiving this medication.

Before taking Bryhali, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

• have had irritation or other skin reaction to a steroid medicine in the past.
• have a skin infection. You may need medicine to treat the skin infection before using Bryhali.
• have diabetes.
• have adrenal gland problems.
• have liver problems.
• are pregnant or plan to become pregnant. It is not known if Bryhali will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if Bryhali passes into your breast milk. If you use Bryhali and breastfeed, do not apply Bryhali to your nipple or areola to avoid getting Bryhali into your baby’s mouth.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are pregnant or plan to become pregnant.

In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child. Talk to your doctor about the risks of using Bryhali to your unborn baby.

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Bryhali crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Bryhali.

• Use Bryhali exactly as your doctor tells you to use it.
• Apply a thin layer of Bryhali to the affected areas 1 time each day and rub in gently.
• You should not use more than 50 g of Bryhali in 1 week.
• Do not bandage, wrap, or cover the treated skin area(s) unless your doctor tells you to.
• Avoid using Bryhali on your face, groin, or underarms (armpits).
• Talk to your doctor if your skin does not improve after 8 weeks of treatment with Bryhali.
• You should not use Bryhali longer than 8 weeks unless your doctor tells you to.
• Wash your hands after using Bryhali unless you are using the medicine to treat your hands.

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

• The condition being treated
• Other medical conditions you have
• Other medications you are taking
• How you respond to this medication

Apply a thin layer of Bryhali lotion to the affected area for the treatment of plaque psoriasis in adults.

If you think you used too much Bryhali, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

• Store Bryhali at room temperature between 68° to 77°F (20° to 25°C). 

• Protect from freezing.

• Keep this and all medicines out of the reach of children.