A long term disease named  Ankylosing   Spondylitis has been linked to a higher risk of cardiovascular problems. A number of factors could be responsible for this increased risk, including the drugs used to treat this painful condition.

No two patients with ankylosing spondylitis are exactly the same. As such, a drug treatment that works for one patient may not work for the other. When one drug isn't working out, patients may turn to another drug.